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Cohortes & Bio collections
Qu'il s'agisse de la NAFLD ou du cancer du foie, notre recherche clinique bénéficie de l'analyse statistique experte de grandes cohortes de patients. HIFIH a lancé et coordonné des collaborations locales, régionales et nationales fournissant de grandes cohortes de patients avec des bio-banques.
|
Name |
Patients |
Design |
Sample size |
Data |
Resources |
|---|---|---|---|---|---|
|
SNIFF |
Chronic liver diseases |
Monocentric (Angers) Longitudinal Clinical care |
8,000 |
· Biology (with specialized biomarkers) · VCTE |
Serum |
|
SNIFF biopsy |
NAFLD |
Monocentric (Angers) Longitudinal Clinical care |
700 |
· Histology · Auto-questionnaires · Biology (with specialized biomarkers) · VCTE (Fibroscan), pSWE (Siemens), 2D-SWE (Aixporer), MRE (Siemens) |
Serum, plasma, DNA Stools, urines |
|
FRESH |
NAFLD |
Multicentric (16 French tertiary care centers) Cross-sectional |
1,000 (Included: 650) |
· Histology · Biology (with specialized biomarkers) · VCTE (Fibroscan) |
Serum, plasma, DNA |
|
METABOL |
Metabolic patients |
Monocentric (Angers: hepatology, diabetology, pneumology) Cross-sectional |
564 |
· Auto-questionnaires · Biology (with specialized biomarkers) · VCTE, MRI-PDFF · Polysomnography · Vascular functional explorations |
Serum, DNA |
|
TATOOINE |
Patients with metabolic risk factors |
Multicentric (6 French tertiary care centers) Longitudinal |
400,000 To be started |
· Biology · VCTE · Clinical events (PMSI codes) |
- |
|
SOPRANO |
Metabolic /alcoholic patients |
Multicentric (10 French primary care centers) |
1,800 To be started |
· Biology (with specialized biomarkers) · VCTE |
Serum |
|
TRAFIC |
NAFLD |
Multicentric (12 French tertiary care centers) Cross-sectional |
1,045 To be started |
· Histology · Biology (with specialized biomarkers) · VCTE |
Serum, plasma, DNA |
|
VEB6 |
Chronic liver diseases |
Multicentric (47 international tertiary care centers) Cross-sectional |
4,132 |
· UGI endoscopy · VCTE · Biiology |
Clinical data |
|
SNIFF CHC |
Hepatocellular carcinoma |
Monocentric (Angers) Longitudinal Clinical care |
100 |
· Histology · Auto-questionnaires · Biology (with specialized biomarkers) · VCTE (Fibroscan) |
Serum, plasma, DNA Stools, urines |
|
CHIC |
suspect liver nodules on cirrhosis / Hepatocellular carcinoma |
Multicentric (17 French tertiary centers) |
500 |
· CT, MR, CEUS |
DICOM images |
